Description

[2-Amino-2-(2-Bromo-Phenyl)-Ethyl]-Carbamic Acid tert-Butyl Ester Hydrochloride is a high-purity, advanced pharmaceutical intermediate primarily used in the synthesis of complex active pharmaceutical ingredients (APIs). This compound matters because it provides a critical, structurally defined building block essential for research and development in medicinal chemistry, enabling the creation of novel therapeutic agents. It is specifically needed by pharmaceutical R&D laboratories, contract research and manufacturing organizations (CROs/CMOs), and fine chemical suppliers focused on producing targeted, small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Employed in multi-step synthetic routes for the production of complex, high-value active pharmaceutical ingredients requiring a bromo-phenyl and protected amino-ethyl motif.
• Process Chemistry Development: Serves as a standardized starting material for scaling up and optimizing synthetic pathways from laboratory to pilot plant scale.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CMOs for the custom synthesis of proprietary compounds and reference standards.
• Academic Research: Utilized in university and institutional laboratories for studies in organic synthesis methodology and pharmacological agent development.

Basic Information

Item	Details
Product Name	[2-Amino-2-(2-Bromo-Phenyl)-Ethyl]-Carbamic Acid tert-Butyl Ester Hydrochloride
CAS No.	939760-41-5
Molecular Formula	C13H19BrClN2O2
Molecular Weight	347.66 g/mol
Synonyms	tert-Butyl N-[2-amino-2-(2-bromophenyl)ethyl]carbamate hydrochloride; (2-Amino-2-(2-bromophenyl)ethyl)carbamic acid 1,1-dimethylethyl ester hydrochloride; 2-Bromo-α-[(tert-butoxycarbonyl)amino]benzenee thanamine hydrochloride; BOC-2-Br-Phe-NH2·HCl; N-Boc-2'-bromo-2-amino-1-phenylethane hydrochloride; N-(tert-Butoxycarbonyl)-2'-bromo-2-phenylethylenediamine hydrochloride
EINECS	Contact for details

Quality Control

Our [2-Amino-2-(2-Bromo-Phenyl)-Ethyl]-Carbamic Acid tert-Butyl Ester Hydrochloride is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your regulatory and R&D documentation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.