Description

[2-(4-Methylphenyl)-2-Hydroxyethyl]-Carbamic Acid 1,1-Dimethylethyl Ester is a specialized organic compound featuring a carbamate-protected amino alcohol moiety attached to a p-tolyl group. This molecular architecture makes it a valuable protected intermediate and building block in advanced synthetic chemistry. It is primarily required by pharmaceutical R&D and fine chemical synthesis teams for constructing complex molecules, including potential active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those requiring a protected amino alcohol functional group.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where specific stereochemistry and functional group protection are critical.
• Peptidomimetics Research: Serves as a precursor or scaffold in the design and synthesis of peptide-like molecules for biological studies.
• Chiral Synthesis: Employed in asymmetric synthesis routes to introduce chiral centers or as a resolving agent due to its stereogenic center.
• Polymer Chemistry: Can act as a monomer or chain extender in the synthesis of specialized polyurethanes or polycarbonates with unique properties.
• Chemical Biology Probes: Utilized in the development of molecular probes and tags for studying biological processes.

Basic Information

Product Name	[2-(4-Methylphenyl)-2-Hydroxyethyl]-Carbamic Acid 1,1-Dimethylethyl Ester
CAS No.	939757-27-4
Molecular Formula	C14H21NO3
Molecular Weight	251.32 g/mol
Synonyms	tert-Butyl N-[2-hydroxy-2-(4-methylphenyl)ethyl]carbamate; N-Boc-2-amino-1-(4-methylphenyl)ethanol; 1-(4-Methylphenyl)-2-[(tert-butoxycarbonyl)amino]ethanol; Boc-4-Methyl-DL-phenylalaninol; N-(tert-Butoxycarbonyl)-2-amino-2-(4-methylphenyl)ethanol; 2-[(tert-Butoxycarbonyl)amino]-1-(p-tolyl)ethanol; BOC-AMINO-(4-METHYL-PHENYL)-ETHANOL; (RS)-2-[(tert-Butoxycarbonyl)amino]-1-(4-methylphenyl)ethanol
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to verify identity, purity, and consistency. Certificates of Analysis (COA) are available upon request, detailing batch-specific results for all critical parameters. Our commitment to quality supports applications in cGMP and research environments where material integrity is paramount.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.