Description

trans-Cotinine Amide is a high-purity, synthetic organic compound derived from cotinine, a major metabolite of nicotine. This specialized amide derivative is valued for its role as a key intermediate and reference standard in advanced pharmaceutical and biochemical research. It is primarily utilized by R&D laboratories and manufacturers in the pharmaceutical, analytical, and life science sectors for developing novel therapeutic agents and diagnostic assays.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel nicotinic receptor modulators and other bioactive molecules.
• Reference Standard: Used for analytical method development, validation, and quality control in pharmaceutical testing and forensic toxicology.
• Biochemical Research: Serves as a tool compound for studying nicotine metabolism, pharmacokinetics, and related neurological pathways.
• Metabolite Studies: Employed in the development of diagnostic kits and assays for detecting and quantifying nicotine-derived metabolites.
• Academic Research: Utilized in universities and research institutes for pharmacological and chemical investigations.

Basic Information

Item	Details
Product Name	trans-Cotinine Amide
CAS No.	939437-34-0
Molecular Formula	C11H13N3O
Molecular Weight	203.24 g/mol
Synonyms	trans-5'-Carbamoylcotinine; (5S)-1-Methyl-5-(3-pyridinyl)-2-pyrrolidinone-5-carboxamide; Cotinine-5-carboxamide; Cotinine Amide; 5-Carbamoylcotinine; 1-Methyl-5-(pyridin-3-yl)-5-carbamoylpyrrolidin-2-one; trans-1-Methyl-5-(3-pyridyl)-5-carbamoyl-2-pyrrolidinone
EINECS	Contact for details

Quality Control

Our trans-Cotinine Amide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with in-house specifications suitable for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.