Description

1,4-Dioxino[2,3-g]quinoline-8-carboxaldehyde, 2,3,6,7-tetrahydro-6-methyl-7-oxo- is a high-purity, advanced pharmaceutical intermediate characterized by its complex fused-ring quinoline structure. This compound is of significant value for its role as a key building block in the synthesis of novel, biologically active molecules, particularly within medicinal chemistry research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex heterocyclic scaffolds.

Application

This specialized intermediate serves critical functions in advanced organic synthesis. Its primary applications include:

• Pharmaceutical Intermediate: A crucial precursor for the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, or oncology.
• Medicinal Chemistry Building Block: Used to construct complex quinoline and dioxino-quinoline based libraries for high-throughput screening (HTS) and structure-activity relationship (SAR) studies.
• Agrochemical Research: Serves as a starting material for developing new active ingredients for crop protection products, leveraging its heterocyclic core.
• Organic Synthesis Reagent: Employed in academic and industrial laboratories for methodological development and the synthesis of novel fused heterocyclic compounds.
• Chemical Reference Standard: Used as a high-purity analytical standard for quality control and method validation in API (Active Pharmaceutical Ingredient) manufacturing.

Basic Information

Product Name	1,4-Dioxino[2,3-g]quinoline-8-carboxaldehyde, 2,3,6,7-tetrahydro-6-methyl-7-oxo-
CAS No.	937658-64-5
Molecular Formula	C14H13NO4
Molecular Weight	259.26 g/mol
Synonyms	6-Methyl-7-oxo-2,3,6,7-tetrahydro-1,4-dioxino[2,3-g]quinoline-8-carbaldehyde; 1,4-Dioxino[2,3-g]quinoline-8-carboxaldehyde, 2,3,6,7-tetrahydro-6-methyl-7-oxo-; 8-Formyl-6-methyl-2,3,6,7-tetrahydro-1,4-dioxino[2,3-g]quinolin-7-one; CAS 937658-64-5; Tetrahydro-dioxinoquinoline carboxaldehyde derivative; Advanced quinoline aldehyde intermediate.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and full analytical data is provided with each shipment to guarantee traceability and consistency for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive nature and potential for oxidation, prolonged exposure to light, heat, or air should be avoided. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area Percent)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.