Description

2,4,6-Trifluoro-n-Methoxy-n-Methylbenzenecarboxamide is a high-purity fluorinated aromatic amide building block. This compound is valued for its unique trifluoromethyl and methoxy substitution pattern, which imparts specific electronic and steric properties critical for advanced synthesis. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the production of specialty polymers and advanced organic electronic materials.
• Ligand Synthesis: Employed in the preparation of novel ligands for catalysis, including transition metal complexes used in cross-coupling reactions.
• Fluorine Chemistry Studies: An important substrate for investigating structure-activity relationships (SAR) and novel fluorination methodologies in academic and industrial R&D.

Basic Information

Product Name	2,4,6-Trifluoro-n-Methoxy-n-Methylbenzenecarboxamide
CAS No.	937602-31-8
Molecular Formula	C10H9F3N2O2
Molecular Weight	246.19 g/mol
Synonyms	N-Methoxy-N-methyl-2,4,6-trifluorobenzamide; 2,4,6-Trifluoro-N-methoxy-N-methylbenzamide; 2,4,6-Trifluorobenzamide, N-methoxy-N-methyl-; N-Methoxy-N-methyl-2,4,6-trifluorobenzenecarboxamide; 937602-31-8; N-Methoxy-N-methyl-2,4,6-trifluoro-benzamide; N-Methoxy-N-methyl-2,4,6-trifluorobenzamide (Weinreb Amide)
EINECS	Contact for details

Quality Control

Our 2,4,6-Trifluoro-n-Methoxy-n-Methylbenzenecarboxamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.