Description

3-((3-Bromophenyl)Ethynyl)Phenol is a high-purity, functionalized phenolic compound featuring a brominated aromatic ring and an ethynyl linker. This unique molecular architecture makes it a valuable advanced intermediate for synthesizing complex organic molecules, particularly in pharmaceutical and materials science research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel drug candidates, ligands, and functional polymers.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential active pharmaceutical ingredients (APIs), especially those targeting kinase inhibition or other bromine/alkyne-dependent pharmacophores.
• Agrochemical Research: Used in developing novel herbicides, fungicides, or plant growth regulators where the bromophenol moiety is critical for bioactivity.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the production of specialty polymers, resins, or liquid crystals with tailored optical or electronic properties.
• Chemical Synthesis Reagent: Employed in Sonogashira coupling and other palladium-catalyzed cross-coupling reactions to introduce functionalized aromatic systems.
• Ligand Synthesis: Useful for constructing complex chelating ligands for catalysis or metal-organic frameworks (MOFs).
• Life Sciences Probe Development: Can be utilized to create fluorescent or bioactive probes for biochemical and cellular assays.

Basic Information

Item	Details
Product Name	3-((3-Bromophenyl)Ethynyl)Phenol
CAS No.	937593-03-8
Molecular Formula	C14H9BrO
Molecular Weight	273.13 g/mol
Synonyms	3-(3-Bromophenylethynyl)phenol; 3-[(3-Bromophenyl)ethynyl]phenol; 3-(3-Bromophenyl-1-yn-1-yl)phenol; 1-Bromo-3-[(3-hydroxyphenyl)ethynyl]benzene; 3-Hydroxy-3'-bromodiphenylacetylene; (3-Bromophenyl)(3-hydroxyphenyl)acetylene; Phenol, 3-[(3-bromophenyl)ethynyl]-; 937593-03-8
EINECS	Contact for details

Quality Control

Every batch of 3-((3-Bromophenyl)Ethynyl)Phenol is manufactured and tested under a strict quality management system. We guarantee high purity and batch-to-batch consistency through rigorous analytical protocols including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to ensure it meets your specific research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under an inert atmosphere if prolonged exposure is anticipated.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.