Description

3′-Phosphoadenosine-5′-Phosphosulfate Triethylammonium Salt is a high-purity, biologically active nucleotide cofactor essential for enzymatic sulfation reactions. This compound serves as the universal sulfate donor in the biosynthesis of sulfated biomolecules, including glycosaminoglycans, steroids, and xenobiotics. It is a critical reagent for researchers and manufacturers in pharmaceutical development, biochemical research, and enzyme characterization, where precise control over sulfotransferase activity is required.

Application

• Sulfotransferase Enzyme Assays: Essential co-substrate for in vitro activity studies and high-throughput screening of enzyme inhibitors.
• Biochemical Research: Used to study sulfate metabolism, phase II drug conjugation pathways, and the biosynthesis of heparan sulfate and other proteoglycans.
• Pharmaceutical Development: Critical for the synthesis and testing of sulfated drug candidates and prodrugs.
• Diagnostic Reagent Manufacturing: Component in diagnostic kits for measuring sulfotransferase activity in clinical samples.
• Metabolite Synthesis: Used to generate sulfated metabolites for standards in analytical chemistry (LC-MS, HPLC) and toxicology studies.
• Cell Culture & Glycobiology: Supports studies on cell surface sulfation and its role in cell signaling, growth, and development.

Basic Information

Product Name	3′-Phosphoadenosine-5′-Phosphosulfate Triethylammonium Salt
CAS No.	936827-87-1
Molecular Formula	C14H22N6O16P2S · x(C6H15N)
Molecular Weight	~507.31 (Free acid) + Triethylammonium counterion
Synonyms	PAPS Triethylammonium Salt; 3'-Phosphoadenylyl sulfate; Adenosine 3'-phosphate 5'-phosphosulfate; PAPS; 3'-Phospho-5'-adenylyl sulfate; Sulfate donor coenzyme; 3'-Phosphoadenosine 5'-phosphosulfuric acid triethylammonium salt
EINECS	Contact for details

Quality Control

Our 3′-Phosphoadenosine-5′-Phosphosulfate Triethylammonium Salt is manufactured under strict quality systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and bioprocessing. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This material is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Assay (Enzymatic)	≥ 90% (as PAPS)
Water Content (KF)	≤ 5.0 %
Triethylammonium Content	Balance

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.