Description

3-(2,2-Difluoro-Ethoxy)-4,5-Difluoro-Benzeneboronic Acid is a highly functionalized boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and advanced materials sectors, particularly for developing active pharmaceutical ingredients (APIs) and organic electronic materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used to create advanced, high-performance active ingredients for crop protection products.
• Material Science: Serves as a monomer or building block for synthesizing specialty polymers, liquid crystals, and organic semiconductors.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D labs exploring new coupling methodologies and complex molecule synthesis.
• Diagnostic Reagent Manufacturing: Employed in the production of specialized biochemical probes and assay components.

Basic Information

Product Name	3-(2,2-Difluoro-Ethoxy)-4,5-Difluoro-Benzeneboronic Acid
CAS No.	936250-23-6
Molecular Formula	C10H9BF4O3
Molecular Weight	264.00 g/mol
Synonyms	4,5-Difluoro-3-(2,2-difluoroethoxy)benzeneboronic Acid; [3-(2,2-Difluoroethoxy)-4,5-difluorophenyl]boronic Acid; 3-(2,2-Difluoroethoxy)-4,5-difluorophenylboronic Acid; 936250-23-6; Boronic acid, B-[3-(2,2-difluoroethoxy)-4,5-difluorophenyl]-; 4,5-Difluoro-3-(2,2-difluoroethoxy)phenylboronic Acid
EINECS	Contact for details

Quality Control

Our 3-(2,2-Difluoro-Ethoxy)-4,5-Difluoro-Benzeneboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality parameters to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.