Description

2-Bromo-3,4-Difluoroanisole is a high-purity, multi-functional aromatic building block of significant importance in advanced organic synthesis. Its core value lies in the strategic placement of bromine and fluorine substituents on the anisole ring, enabling precise molecular modifications and serving as a key precursor for complex heterocyclic systems. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is utilized to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the difluoroanisole moiety contributes to improved biological activity and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorine-containing aromatic cores in electronic materials, enhancing thermal stability and optoelectronic properties.
• Cross-Coupling Reactions: The bromine atom acts as an excellent handle for palladium-catalyzed reactions (e.g., Suzuki, Stille, Negishi) for constructing complex biaryl structures.
• Functional Material Research: Employed in academic and industrial R&D for creating novel polymers, ligands, and specialty chemicals with tailored properties.

Basic Information

Product Name	2-Bromo-3,4-Difluoroanisole
CAS No.	935285-66-8
Molecular Formula	C7H5BrF2O
Molecular Weight	223.02 g/mol
Synonyms	1-Bromo-2,3-difluoro-4-methoxybenzene; 2,3-Difluoro-4-methoxybromobenzene; Benzene, 1-bromo-2,3-difluoro-4-methoxy-; 4-Methoxy-2,3-difluorobromobenzene; 2-Bromo-3,4-difluoro-1-methoxybenzene; Anisole, 2-bromo-3,4-difluoro-
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-3,4-Difluoroanisole is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and high purity. Our standard grade meets typical research and development specifications, with comprehensive Certificates of Analysis (COA) provided for each shipment. We support custom synthesis and can tailor purity levels (e.g., >97%, >98%, >99%) to meet specific project requirements under cGMP or ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider using an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.