Description

Ethanone, 1-[2-Amino-5-(Trifluoromethoxy)Phenyl]-2-Chloro- is a high-purity, advanced pharmaceutical intermediate characterized by its distinct trifluoromethoxy and chloro-substituted aromatic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular modification. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel Active Pharmaceutical Ingredients (APIs), especially for central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides, where the trifluoromethoxy group can enhance biological activity and environmental stability.
• Material Science: Serves as a precursor for specialty polymers and liquid crystals, contributing to advanced material properties.
• Organic Synthesis: An important reagent for constructing complex aromatic systems in medicinal and process chemistry.
• Fluorine Chemistry: A valuable substrate for studying structure-activity relationships (SAR) in fluorinated compounds.

Basic Information

Product Name	Ethanone, 1-[2-Amino-5-(Trifluoromethoxy)Phenyl]-2-Chloro-
CAS No.	934829-56-8
Molecular Formula	C9H7ClF3NO2
Molecular Weight	253.61 g/mol
Synonyms	2-Chloro-1-[2-amino-5-(trifluoromethoxy)phenyl]ethanone; 1-(2-Amino-5-(trifluoromethoxy)phenyl)-2-chloroethanone; 2-Chloro-1-(2-amino-5-(trifluoromethoxyphenyl)ethan-1-one; 2-Amino-5-(trifluoromethoxy)phenacyl chloride; α-Chloro-2-amino-5-(trifluoromethoxy)acetophenone
EINECS	Contact for details

Quality Control

Our Ethanone, 1-[2-Amino-5-(Trifluoromethoxy)Phenyl]-2-Chloro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all specified parameters. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.