Description

2-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}[(1S)-1-Phenylethyl]Amino)Acetic Acid is a sophisticated chiral building block and protected amino acid derivative, essential for advanced organic synthesis. Its core value lies in enabling the precise construction of complex peptides and pharmaceutical intermediates with high stereochemical fidelity. This compound is critically needed by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutic agents and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for peptide-based drugs.
• Peptide Synthesis: Serves as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis (SPPS), where the Fmoc group provides orthogonal protection.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or building block in asymmetric synthesis to induce stereoselectivity in carbon-carbon and carbon-heteroatom bond-forming reactions.
• Proteomics Research: Used in chemical biology and proteomics for labeling, cross-linking, or modifying peptides and proteins to study structure and function.
• Fine Chemical Production: Employed in the custom synthesis of complex organic molecules, including catalysts, ligands, and specialty polymers.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry laboratories worldwide.

Basic Information

Product Name	2-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}[(1S)-1-Phenylethyl]Amino)Acetic Acid
CAS No.	934752-38-2
Molecular Formula	C25H23NO4
Molecular Weight	401.46 g/mol
Synonyms	N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-[(1S)-1-phenylethyl]glycine; Fmoc-N-[(1S)-1-Phenylethyl]glycine; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(1-phenylethyl)amino)acetic acid; N-α-Fmoc-N-α-[(1S)-1-phenylethyl]glycine; Fmoc-(S)-1-Phenylethylglycine; N-Fmoc-N-(1-phenylethyl)glycine (S-isomer); (S)-N-Fmoc-N-(1-phenylethyl)aminoacetic acid
EINECS	Contact for details

Quality Control

Our 2-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}[(1S)-1-Phenylethyl]Amino)Acetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and fine chemical synthesis. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a desiccated environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.