Description

4-(4-Ethynylbenzyl)Morpholine is a high-value, specialized organic building block featuring both a morpholine ring and a terminal alkyne functional group. This unique bifunctional structure makes it a critical intermediate for the synthesis of complex molecules in advanced research and development. It is primarily sought after by pharmaceutical, agrochemical, and material science industries for applications in medicinal chemistry, catalyst design, and polymer modification.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in the development of kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in creating novel active ingredients for crop protection products.
• Material Science: Serves as a monomer or cross-linker in the development of specialty polymers and advanced materials with tailored properties.
• Click Chemistry: The terminal alkyne group enables efficient Huisgen 1,3-dipolar cycloaddition (click) reactions for bioconjugation and polymer functionalization.
• Ligand Synthesis: Utilized in the preparation of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology: Employed as a probe or linker in the development of chemical tools for studying biological systems.

Basic Information

Product Name	4-(4-Ethynylbenzyl)Morpholine
CAS No.	933936-59-5
Molecular Formula	C13H15NO
Molecular Weight	201.27 g/mol
Synonyms	4-[(4-Ethynylphenyl)methyl]morpholine; N-[(4-Ethynylphenyl)methyl]morpholine; 4-(4-Ethynylbenzyl)morpholine; Morpholine, 4-[(4-ethynylphenyl)methyl]-; 933936-59-5; 4-(4-Ethynyl-benzyl)-morpholine
EINECS	Contact for details

Quality Control

Our 4-(4-Ethynylbenzyl)Morpholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee it meets the rigorous standards required for research and commercial synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.