Description

1,2-Difluoro-4-Methoxy-5-Methyl-Benzene is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. Its unique substitution pattern makes it a valuable precursor for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is primarily sought by R&D chemists and process development scientists for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially those requiring fluorinated aromatic cores to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the difluoro-methoxy-methyl benzene scaffold imparts specific biological activity.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs) due to its influence on electronic properties and stability.
• Organic Synthesis & Catalysis: Employed in cross-coupling reactions and as a ligand precursor in catalytic systems, leveraging the fluorine atoms for electronic tuning.
• Polymer & Resin Modifier: Incorporated into specialty polymers to enhance chemical resistance, thermal stability, and surface properties.

Basic Information

Product Name	1,2-Difluoro-4-Methoxy-5-Methyl-Benzene
CAS No.	933674-84-1
Molecular Formula	C8H8F2O
Molecular Weight	158.15 g/mol
Synonyms	4-Methoxy-5-methyl-1,2-difluorobenzene; 1,2-Difluoro-4-methoxy-5-methylbenzene; 5-Methyl-1,2-difluoro-4-methoxybenzene; Benzene, 1,2-difluoro-4-methoxy-5-methyl-; 2,3-Difluoro-4-methoxytoluene
EINECS	Contact for details

Quality Control

Our 1,2-Difluoro-4-Methoxy-5-Methyl-Benzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are provided with every shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.