Description

1-Chloro-2-Methyl-3-Trifluoromethoxy-Benzene is a high-purity fluorinated aromatic building block of significant interest in advanced chemical synthesis. Its unique structure, combining chloro, methyl, and trifluoromethoxy substituents, makes it a versatile intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by R&D and production teams in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic cores for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group can improve pesticidal activity and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated components for electronic display materials and organic light-emitting diodes (OLEDs).
• Functional Material Development: Employed in creating specialty polymers, coatings, and advanced materials that benefit from the introduction of fluorine atoms for specific chemical resistance or surface properties.
• Organic Synthesis & Catalysis Research: A valuable substrate in academic and industrial research for studying cross-coupling reactions and developing new catalytic methodologies involving halogenated arenes.

Basic Information

Product Name	1-Chloro-2-Methyl-3-Trifluoromethoxy-Benzene
CAS No.	933674-78-3
Molecular Formula	C9H6ClF3O
Molecular Weight	222.59 g/mol
Synonyms	3-Chloro-2-methyl-1-(trifluoromethoxy)benzene; 2-Methyl-3-chloro-1-(trifluoromethoxy)benzene; 1-Chloro-2-methyl-3-(trifluoromethoxy)benzene; Benzene, 1-chloro-2-methyl-3-(trifluoromethoxy)-; 3-(Trifluoromethoxy)-2-chlorotoluene; 2-Chloro-6-methyl-1-(trifluoromethoxy)benzene; 2-Methyl-3-chloroanisole, 3-trifluoromethyl ether
EINECS	Contact for details

Quality Control

Our 1-Chloro-2-Methyl-3-Trifluoromethoxy-Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.