Description

3-Ethoxy-4-Iodobenzonitrile is a versatile halogenated aromatic nitrile building block. This compound is valued for its unique molecular architecture, which combines an electron-donating ethoxy group with an electron-withdrawing nitrile and a reactive iodine atom, making it a key intermediate in advanced synthesis. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical sectors for constructing complex molecules, particularly in cross-coupling reactions and as a precursor for functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators, leveraging its halogenated aromatic core.
• Material Science Research: Serves as a precursor in the development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Heck couplings to form new carbon-carbon bonds.
• Ligand and Catalyst Development: Utilized in the design and synthesis of novel ligands and organocatalysts for asymmetric synthesis.
• Chemical Biology Probes: Acts as a starting material for creating tagged molecules and probes used in biochemical assays and diagnostic research.

Basic Information

Product Name	3-Ethoxy-4-Iodobenzonitrile
CAS No.	933585-40-1
Molecular Formula	C9H8INO
Molecular Weight	273.07 g/mol
Synonyms	4-Iodo-3-ethoxybenzonitrile; 3-Ethoxy-4-iodobenzonitrile; Benzonitrile, 3-ethoxy-4-iodo-; 4-Cyano-2-ethoxyiodobenzene; 2-Ethoxy-4-cyanoidobenzene; 933585-40-1; 3-Ethoxy-4-iodo-benzonitrile
EINECS	Contact for details

Quality Control

Every batch of 3-Ethoxy-4-Iodobenzonitrile is produced under a strict quality management system. Our products undergo rigorous quality testing, including HPLC, NMR, and GC-MS analysis, to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.