Description

3-Chloropropiononitrile is a versatile and reactive bifunctional organic intermediate, serving as a critical building block in advanced chemical synthesis. Its value lies in the presence of both a reactive nitrile group and a chloromethyl moiety, enabling a wide range of nucleophilic substitution and cyclization reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for the synthesis of heterocyclic compounds, active pharmaceutical ingredients (APIs), and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various heterocyclic compounds and active pharmaceutical ingredients (APIs), including potential antiviral and anticancer agents.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and plant growth regulators, leveraging its reactivity to construct complex molecular frameworks.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for specialty polymers, resins, and functional materials with tailored properties.
• Organic Synthesis Building Block: Employed in cyanoethylation reactions and as a starting material for synthesizing amino acids, diamines, and other fine chemicals.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new reaction pathways and developing novel chemical entities.

Basic Information

Product Name	3-Chloropropiononitrile
CAS No.	542-76-7
Molecular Formula	C3H4ClN
Molecular Weight	89.52 g/mol
Synonyms	3-Chloropropanenitrile; β-Chloropropionitrile; 2-Chloroethyl cyanide; 3-Chloropropionitrile; Chloroacetonitrile, 2-chloro-; USAF EK-553; NSC 8815; UN 2810
EINECS	208-828-5

Quality Control

Our 3-Chloropropiononitrile is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, and we support compliance with global regulatory standards including REACH. Specifications can be adjusted to meet specific customer requirements for research or commercial-scale projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.4360 - 1.4400
Density (20°C)	1.14 - 1.16 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.