Description

Chloroacetonitrile is a versatile and highly reactive bifunctional organic intermediate, serving as a critical building block in fine chemical synthesis. Its value lies in the presence of both a reactive nitrile group and a chloromethyl group, enabling a wide range of nucleophilic substitution and cyclization reactions. This compound is essential for manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to synthesize complex molecules efficiently.

Application

• Pharmaceutical Intermediates: Key precursor in the synthesis of various heterocyclic compounds, including pyrimidines, triazoles, and thiazoles, which are core structures in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators, where it acts as a linker to introduce the cyanoacetate moiety.
• Dye and Pigment Manufacturing: Serves as a starting material for certain cyanine dyes and other colorants requiring a reactive chloromethyl handle.
• Chemical Research & Development: A valuable reagent in organic synthesis labs for constructing C-C and C-N bonds, particularly in the preparation of α-substituted acetonitriles.
• Polymer Modifiers: Employed in the synthesis of specialty monomers and as a cross-linking agent or chain transfer agent in certain polymerization processes.

Basic Information

Product Name	Chloroacetonitrile
CAS No.	107-14-2
Molecular Formula	C2H2ClN
Molecular Weight	75.50 g/mol
Synonyms	Chloromethyl cyanide; Monochloroacetonitrile; Cyanomethyl chloride; 2-Chloroacetonitrile; Chloroethanenitrile; α-Chloroacetonitrile; Chloracetonitrile; USAF EK-553
EINECS	203-465-6

Quality Control

Our Chloroacetonitrile is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting our customers' needs in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong bases and oxidizing agents. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use. Recommended storage temperature is 2-8°C for extended stability, though short-term storage at controlled room temperature (15-25°C) is acceptable.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.420 - 1.425
Density (20°C)	1.18 - 1.20 g/mL
Boiling Point	124 - 126 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.