Description

cis-2-tert-Butyl-2-Butenedinitrile is a specialized organic nitrile compound characterized by its cis-configured double bond and bulky tert-butyl substituent. This unique structure makes it a valuable intermediate in advanced organic synthesis, particularly for constructing complex molecular frameworks. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for candidates requiring sterically hindered, functionalized olefin structures.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where its nitrile functionality can be transformed into various heterocycles or amides.
• Material Science Research: Serves as a monomer or precursor for developing specialized polymers, resins, or liquid crystals with tailored properties.
• Organic Synthesis Reagent: Employed in Diels-Alder reactions, Michael additions, and other cyclization processes to introduce the tert-butyl group and nitrile functionality into target molecules.
• Chemical Research & Development: A versatile scaffold for methodology development and exploring new reaction pathways in academic and industrial R&D laboratories.

Basic Information

Product Name	cis-2-tert-Butyl-2-Butenedinitrile
CAS No.	169309-80-2
Molecular Formula	C8H10N2
Molecular Weight	134.18 g/mol
Synonyms	(Z)-2-tert-Butyl-2-butenedinitrile; (Z)-2-(tert-Butyl)but-2-enedinitrile; cis-2-(1,1-Dimethylethyl)-2-butenedinitrile; 2-tert-Butyl-2-butenedinitrile (cis-); (Z)-2-(1,1-Dimethylethyl)-2-butenedinitrile; Butenedinitrile, 2-(1,1-dimethylethyl)-, (Z)-; cis-2-tert-Butylbut-2-enedinitrile
EINECS	Contact for details

Quality Control

Our cis-2-tert-Butyl-2-Butenedinitrile is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for research and commercial-scale material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider maintaining under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.