Description

1-Cyclohexenylisocyanide is a versatile and reactive organic building block featuring an isocyanide functional group attached to a cyclohexene ring. This compound matters for its role as a key precursor in multicomponent reactions, enabling the efficient synthesis of complex heterocyclic scaffolds and natural product analogs. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A critical reagent in the Ugi and Passerini multicomponent reactions for synthesizing diverse pharmacologically active compounds and peptide mimetics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides by creating unique nitrogen-containing heterocycles.
• Material Science: Serves as a monomer or ligand precursor for the development of functional polymers, metal-organic frameworks (MOFs), and catalytic systems.
• Chemical Biology & Proteomics: Employed in bioorthogonal chemistry and activity-based protein profiling (ABPP) due to the reactive isocyanide handle.
• Academic & Discovery Chemistry: A valuable tool in synthetic organic chemistry laboratories for methodology development and the exploration of new chemical space.

Basic Information

Product Name	1-Cyclohexenylisocyanide
CAS No.	1121-57-9
Molecular Formula	C7H9N
Molecular Weight	107.15 g/mol
Synonyms	1-Isocyano-1-cyclohexene; Cyclohex-1-en-1-yl isocyanide; 1-Cyclohexenyl isonitrile; 1-Cyclohexene isocyanide; 1-Cyclohexenyl isocyanide; Cyclohexenyl isocyanide; NSC 5188
EINECS	214-345-5

Quality Control

Our 1-Cyclohexenylisocyanide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR analysis, to ensure high purity and consistent performance. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting identity, purity, and impurity profiles. Our quality systems support development from research to commercial scale, ensuring reliability for critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its highly volatile and light-sensitive nature, containers should be kept sealed and allowed to equilibrate to room temperature before opening to minimize moisture ingress and degradation.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.