Description

1-(Hydroxymethyl)Cyclopropaneacetonitrile is a versatile cyclopropane derivative featuring both hydroxymethyl and nitrile functional groups, making it a valuable bifunctional building block in advanced organic synthesis. Its unique structure enables the introduction of a strained cyclopropane ring system while providing orthogonal handles for further chemical elaboration. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Ligand and Catalyst Development: Serves as a backbone for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Monomer: Employed in the research and production of specialized polymers and resins with tailored thermal and mechanical properties.
• Chemical Biology Probe: Utilized as a scaffold for developing molecular probes and tools to study biological pathways and protein functions.
• Fine Chemical Building Block: Integral for the multi-step synthesis of complex natural products, flavors, and fragrances.

Basic Information

Product Name	1-(Hydroxymethyl)Cyclopropaneacetonitrile
CAS No.	152922-71-9
Molecular Formula	C6H9NO
Molecular Weight	111.14 g/mol
Synonyms	2-(1-(Hydroxymethyl)cyclopropyl)acetonitrile; (1-(Hydroxymethyl)cyclopropyl)acetonitrile; Cyclopropaneacetonitrile, 1-(hydroxymethyl)-; 1-Cyclopropanemethanol, α-(cyanomethyl)-; Hydroxymethylcyclopropylacetonitrile; 2-(Hydroxymethylcyclopropyl)acetonitrile; (Hydroxymethylcyclopropyl)acetonitrile
EINECS	Contact for details

Quality Control

Our 1-(Hydroxymethyl)Cyclopropaneacetonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity assessment and structural confirmation, to ensure it meets the high standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, identity, and impurity profiles. We support cGMP and ISO 9001 compliant production for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.