Description

(S)-1-p-Tolylaziridine-2-Carboxamide CAS NO 933453-55-5 is a high-purity, chiral aziridine derivative, a critical building block in asymmetric synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules with precise stereochemistry. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery.
• Agrochemical Research: Used in the development of novel, stereospecific pesticides and herbicides with enhanced efficacy and environmental profiles.
• Asymmetric Catalysis: Serves as a precursor for chiral ligands and catalysts used in enantioselective transformations.
• Organic Synthesis: A versatile building block for constructing nitrogen-containing heterocycles and complex natural product analogs.
• Material Science Research: Potential intermediate in the synthesis of specialty polymers and advanced functional materials.

Basic Information

Product Name	(S)-1-p-Tolylaziridine-2-Carboxamide
CAS No.	933453-55-5
Molecular Formula	C11H14N2O
Molecular Weight	190.24 g/mol
Synonyms	(S)-1-(4-Methylphenyl)aziridine-2-carboxamide; (2S)-1-(4-Methylphenyl)aziridine-2-carboxamide; (S)-1-(p-Tolyl)aziridine-2-carboxamide; (S)-1-(4-Methylphenyl)aziridine-2-carboxylic acid amide; (S)-1-(p-Tolyl)aziridine-2-carboxylic acid amide; (S)-1-(4-Methylphenyl)aziridine-2-carboxylic acid carboxamide; (S)-1-(4-Methylphenyl)aziridine-2-carboxamide
EINECS	Contact for details

Quality Control

Our (S)-1-p-Tolylaziridine-2-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and standard spectroscopic methods for identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, chiral excess, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.