Description

Z-Dl-Gln-Oh CAS NO 932735-43-8 is a protected glutamine derivative, specifically the Z-protected form of DL-glutamine. This compound serves as a crucial chiral building block and intermediate in advanced organic synthesis, particularly in peptide chemistry and pharmaceutical research. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require high-purity, specialized amino acid derivatives for drug discovery and development.

Application

• Peptide Synthesis: Used as a protected glutamine residue in solid-phase and solution-phase peptide synthesis to prevent side reactions.
• Pharmaceutical Intermediates: A key chiral building block in the synthesis of active pharmaceutical ingredients (APIs) and complex drug molecules.
• Biochemical Research: Employed in studies of enzyme substrates, metabolic pathways, and as a precursor for labeled compounds.
• Protecting Group Chemistry: The Z (benzyloxycarbonyl) group allows for selective deprotection, enabling complex multi-step synthetic sequences.
• Fine Chemical Production: Serves as an intermediate in the manufacture of specialty chemicals, catalysts, and ligands.
• Academic & R&D: Utilized in university and corporate research laboratories for developing new synthetic methodologies.

Basic Information

Item	Details
Product Name	Z-Dl-Gln-Oh
CAS No.	932735-43-8
Molecular Formula	C₁₃H₁₆N₂O₅
Molecular Weight	280.28 g/mol
Synonyms	N-Carbobenzoxy-DL-glutamine; Z-DL-Glutamine; N-(Benzyloxycarbonyl)-DL-glutamine; N-Cbz-DL-glutamine; DL-Glutamine, N-[(phenylmethoxy)carbonyl]-; Benzyl N-(DL-4-amino-4-carboxybutyl)carbamate; (RS)-2-[(Benzyloxycarbonyl)amino]-4-carbamoylbutanoic acid; Nα-Carbobenzyloxy-DL-glutamine
EINECS	Contact for details

Quality Control

Our Z-Dl-Gln-Oh is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP guidelines for advanced intermediates. Specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	DL-mixture (Racemic)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.