Description

Benzyl N-[(1R,3S)-3-Fluorocyclopentyl]carbamate is a high-purity chiral building block of significant interest in advanced organic synthesis. This compound matters because it provides a stereodefined, fluorinated cyclopentane scaffold, a privileged structure for modulating the physicochemical and biological properties of target molecules. It is primarily needed by pharmaceutical and agrochemical R&D organizations for the development of novel active ingredients, particularly where the introduction of fluorine is critical for metabolic stability, bioavailability, or binding affinity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, especially in oncology, CNS disorders, and antiviral therapies.
• Agrochemical Synthesis: Used in creating advanced, fluorinated active ingredients for crop protection with potentially enhanced efficacy and environmental profile.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in lead optimization programs.
• Fluorine Chemistry: An important reagent for studying the effects of fluorine substitution on molecular conformation and reactivity in complex organic systems.
• Peptidomimetics: Can be incorporated into peptide backbones to create metabolically stable analogs for biochemical research.
• Catalyst & Ligand Development: Potential precursor for chiral ligands or organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	Benzyl N-[(1R,3S)-3-Fluorocyclopentyl]carbamate
CAS No.	932706-26-8
Molecular Formula	C13H16FNO2
Molecular Weight	237.27 g/mol
Synonyms	Carbamic acid, N-[(1R,3S)-3-fluorocyclopentyl]-, phenylmethyl ester; Benzyl (1R,3S)-3-fluorocyclopentylcarbamate; (1R,3S)-3-Fluorocyclopentyl-carbamic acid benzyl ester; Benzyl N-[(1R,3S)-3-fluorocyclopentyl]carbamate; (1R,3S)-N-Cbz-3-fluorocyclopentanamine; Cbz-(1R,3S)-3-Fluorocyclopentylamine; N-Cbz-3-fluorocyclopentylamine (stereospecific)
EINECS	Contact for details

Quality Control

Our Benzyl N-[(1R,3S)-3-Fluorocyclopentyl]carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC to ensure enantiomeric purity and standard spectroscopic methods for identity confirmation. We provide comprehensive Certificates of Analysis (COA) detailing purity, chiral excess, and impurity profiles to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is sensitive to strong alkalis and fluorides; keep away from incompatible materials. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.