Description

(4-(Hydroxymethyl)-3-(Trifluoromethyl)Phenyl)Boronic Acid is a high-value, multifunctional boronic acid derivative essential for modern synthetic chemistry. Its core value lies in its dual functionality, serving as a versatile building block for Suzuki-Miyaura cross-coupling reactions and as a precursor for further chemical modifications. This compound is critically needed by research scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used to construct complex molecules for novel herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for enhanced biological activity and metabolic stability.
• Suzuki-Miyaura Cross-Coupling: Serves as a critical boronic acid coupling partner for forming carbon-carbon bonds between aromatic rings, a fundamental reaction in medicinal and process chemistry.
• Ligand and Catalyst Development: Utilized in the research and development of novel ligands for transition metal catalysis and organocatalysts.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those for OLEDs and semiconductors, where the boronic acid group enables precise molecular assembly.
• Chemical Biology Probes: Acts as a precursor for synthesizing molecular probes and tags used in bio-conjugation and target identification studies.

Basic Information

Product Name	(4-(Hydroxymethyl)-3-(Trifluoromethyl)Phenyl)Boronic Acid
CAS No.	932390-39-1
Molecular Formula	C8H8BF3O3
Molecular Weight	219.96 g/mol
Synonyms	[4-(Hydroxymethyl)-3-(trifluoromethyl)phenyl]boronic acid; (4-Hydroxymethyl-3-trifluoromethylphenyl)boronic acid; 3-Trifluoromethyl-4-hydroxymethylbenzeneboronic acid; Boronic acid, B-[4-(hydroxymethyl)-3-(trifluoromethyl)phenyl]-; 4-(Hydroxymethyl)-3-(trifluoromethyl)benzeneboronic acid; (3-CF3-4-CH2OH-Ph)B(OH)2
EINECS	Contact for details

Quality Control

Our (4-(Hydroxymethyl)-3-(Trifluoromethyl)Phenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.