Description

5-Bromo-8-Fluoro-2-Methylquinoline is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique halogenated quinoline structure, which serves as a versatile scaffold for constructing complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting neurological disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinoline core.
• Material Science: Serves as a building block for organic light-emitting diodes (OLEDs), liquid crystals, and other advanced functional materials due to its electron-transport properties.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and protein-ligand interactions.
• Catalyst Ligand Synthesis: Utilized to create novel ligands for transition metal catalysts used in cross-coupling and other asymmetric reactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Item	Detail
Product Name	5-Bromo-8-Fluoro-2-Methylquinoline
CAS No.	931414-04-9
Molecular Formula	C₁₀H₇BrFN
Molecular Weight	240.07 g/mol
Synonyms	5-Bromo-8-fluoro-2-methylquinoline; 2-Methyl-5-bromo-8-fluoroquinoline; 8-Fluoro-5-bromo-2-methylquinoline; Quinoline, 5-bromo-8-fluoro-2-methyl-; 931414-04-9; 5-Br-8-F-2-MeQ
EINECS	Contact for details

Quality Control

Our 5-Bromo-8-Fluoro-2-Methylquinoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications. Our quality commitment supports applications requiring GMP starting materials and aligns with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is sensitive to fluoride and strong alkali; ensure it is stored separately from such materials to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.