Description

4-Chloro-2-Iodo-3-Methylthieno[2,3-B]Pyridine-5-Carbonitrile is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. Its unique molecular architecture, featuring halogen and nitrile substituents on a fused thienopyridine core, makes it a critical intermediate for constructing complex pharmacophores and functional materials. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications in drug discovery, ligand synthesis, and the development of novel electronic materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated heterocyclic structure for bioactivity.
• Material Science: Acts as a building block for organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs) due to its electron-deficient pyridine and thiophene rings.
• Chemical Biology: Employed in the creation of molecular probes and labeled compounds for biochemical assays and diagnostic applications.
• Cross-Coupling Reactions: The iodine and chlorine substituents make it an excellent substrate for versatile palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Ligand Synthesis: Utilized for constructing complex chelating ligands in coordination chemistry and catalysis.

Basic Information

Product Name	4-Chloro-2-Iodo-3-Methylthieno[2,3-B]Pyridine-5-Carbonitrile
CAS No.	930293-15-5
Molecular Formula	C9H4ClIN2S
Molecular Weight	334.56 g/mol
Synonyms	4-Chloro-2-iodo-3-methylthieno[2,3-b]pyridine-5-carbonitrile; Thieno[2,3-b]pyridine-5-carbonitrile, 4-chloro-2-iodo-3-methyl-; 930293-15-5; 4-Chloro-2-iodo-3-methylthieno[2,3-b]pyridine-5-carbonitrile; 3-Methyl-4-chloro-2-iodothieno[2,3-b]pyridine-5-carbonitrile
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-2-Iodo-3-Methylthieno[2,3-B]Pyridine-5-Carbonitrile adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and development. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.