Description

tert-Butyl 2-Piperidin-3-Ylpyrrolidine-1-Carboxylate is a sophisticated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because it provides a versatile chiral scaffold for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). Pharmaceutical researchers and fine chemical manufacturers need this high-purity intermediate to accelerate drug discovery programs and process chemistry development.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of complex drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing focused libraries in structure-activity relationship (SAR) studies.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or ligand precursor in catalytic asymmetric transformations.
• Process Chemistry Development: Employed in the scale-up and optimization of synthetic routes for new chemical entities (NCEs).
• Custom Synthesis: A starting material for the contract manufacturing of bespoke, high-value fine chemicals and advanced intermediates.

Basic Information

Product Name	tert-Butyl 2-Piperidin-3-Ylpyrrolidine-1-Carboxylate
CAS No.	929973-31-9
Molecular Formula	C14H26N2O2
Molecular Weight	254.37 g/mol
Synonyms	1-Boc-2-(3-piperidinyl)pyrrolidine; tert-Butyl 2-(piperidin-3-yl)pyrrolidine-1-carboxylate; 2-(3-Piperidinyl)-1-pyrrolidinecarboxylic acid 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-2-(3-piperidinyl)pyrrolidine; 929973-31-9; Pyrrolidine-1-carboxylic acid, 2-(3-piperidinyl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Piperidin-3-Ylpyrrolidine-1-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to meet the stringent requirements of pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The product is stable under inert atmosphere. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.