Description

[(2,3-Dihydro-Indole-1-Carbonyl)-Amino]-Acetic Acid is a specialized organic compound featuring a unique indoline scaffold coupled with a glycine derivative, making it a valuable synthetic intermediate. This compound matters for its role as a key building block in the research and development of novel pharmaceuticals and bioactive molecules, particularly those targeting neurological and metabolic pathways. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of potential drug candidates, especially those containing the privileged indoline structure.
• Protease Inhibitor Research: Used in the development of enzyme inhibitors where the carbonyl-amino-acetic acid moiety can mimic peptide bonds.
• Chemical Biology Probes: Acts as a scaffold for creating molecular probes to study biological processes and protein functions.
• Agrochemical Synthesis: Employed in the research phase for developing new active ingredients with specific biological activity.
• Academic & Institutional R&D: Utilized in university and research institute laboratories for methodological studies and novel compound library generation.
• Peptidomimetic Development: Functions as a building block for designing and synthesizing peptidomimetics, which are molecules that mimic peptides.

Basic Information

Product Name	[(2,3-Dihydro-Indole-1-Carbonyl)-Amino]-Acetic Acid
CAS No.	929967-04-4
Molecular Formula	C11H12N2O3
Molecular Weight	220.23 g/mol
Synonyms	2-[[(2,3-Dihydro-1H-indole-1-carbonyl)amino]acetic acid; N-(Carboxymethyl)-2,3-dihydro-1H-indole-1-carboxamide; Glycine, N-(2,3-dihydro-1H-indol-1-ylcarbonyl)-; 1H-Indole-1-carboxamide, N-(carboxymethyl)-2,3-dihydro-; (Indoline-1-carbonylamino)-acetic acid
EINECS	Contact for details

Quality Control

Our [(2,3-Dihydro-Indole-1-Carbonyl)-Amino]-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay (HPLC), related substances, and residual solvents. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliable performance in your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.