Description

Ac-Arg-Leu-Arg-Amc is a fluorogenic peptide substrate designed for the detection and study of protease activity. This compound is critical for biochemical research and pharmaceutical development, serving as a highly sensitive tool for enzyme kinetics and inhibitor screening. It is primarily needed by research institutions, diagnostic kit manufacturers, and pharmaceutical companies engaged in proteomics and drug discovery.

Application

• Protease Activity Assays: Used as a selective substrate for monitoring the enzymatic activity of specific proteases in vitro.
• High-Throughput Screening (HTS): Employed in pharmaceutical research to identify and characterize potential protease inhibitors for therapeutic development.
• Biochemical Research: A vital tool for studying protease function, specificity, and catalytic mechanisms in academic and industrial laboratories.
• Diagnostic Development: Can be utilized in the development of fluorometric diagnostic tests for diseases where protease levels are a biomarker.
• Enzyme Kinetics Studies: Enables precise measurement of kinetic parameters such as Km and Vmax for target proteases.
• Quality Control in Biomanufacturing: Applied in monitoring the activity and consistency of enzyme preparations used in bioprocessing.

Basic Information

Product Name	Ac-Arg-Leu-Arg-Amc
CAS No.	929903-87-7
Molecular Formula	C30H48N12O6
Molecular Weight	648.78 g/mol
Synonyms	Acetyl-Arg-Leu-Arg-7-Amino-4-methylcoumarin; Ac-RLR-AMC; Ac-Arg-Leu-Arg-AMC; Ac-R-L-R-AMC; Acetyl-L-arginyl-L-leucyl-L-arginyl-7-amido-4-methylcoumarin; Fluorogenic Substrate for Proteases; Protease Substrate 929903-87-7
EINECS	Contact for details

Quality Control

Our Ac-Arg-Leu-Arg-Amc is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and performance in standard assays. We adhere to relevant quality guidelines to support our global customer base in critical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive (store away from light). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF
Functional Activity	Conforms to reference standard

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.