Description

Ceftizoxime is a third-generation cephalosporin antibiotic with a broad spectrum of activity against Gram-positive and Gram-negative bacteria. Its primary value lies in its enhanced stability against β-lactamases, making it a critical agent for treating serious infections where other antibiotics may fail. This product is essential for pharmaceutical manufacturers and research institutions involved in developing injectable antibiotic formulations and conducting microbiological studies.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the formulation of sterile injectable antibiotics for clinical use.
• Hospital Infection Treatment: Targeting infections caused by susceptible organisms, including respiratory tract, urinary tract, skin, and intra-abdominal infections.
• Research & Development: Used as a reference standard in microbiological assays and for studying bacterial resistance mechanisms.
• Veterinary Medicine: Potential application in developing antibiotic treatments for bacterial infections in animals.
• Intermediate Synthesis: Serving as a key intermediate in the synthesis of more complex cephalosporin derivatives.

Basic Information

Product Name	Ceftizoxime
CAS No.	929101-93-9
Molecular Formula	C13H13N5O5S2
Molecular Weight	383.40 g/mol
Synonyms	Ceftizoxime Sodium; FK 749; FR 13749; SKF 88373; Ceftizox; (6R,7R)-7-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid; Antibiotic FR 13749; Epocelin (brand name)
EINECS	Contact for details

Quality Control

Our Ceftizoxime is manufactured under strict quality systems to ensure it meets the high standards required for pharmaceutical applications. Each batch is tested against rigorous specifications for identity, purity, and potency. Certificates of Analysis (COA) are provided, detailing compliance with relevant pharmacopeial standards such as USP/EP where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.2%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Bacterial Endotoxins	< 0.10 EU/mg
Sterility (for sterile grade)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.