Description

Ceftizoxime is a third-generation cephalosporin antibiotic belonging to the β-lactam class. Its primary value lies in its broad-spectrum activity against a wide range of Gram-positive and Gram-negative bacteria, including many β-lactamase-producing strains. This makes it a critical intermediate and active pharmaceutical ingredient (API) for manufacturers in the pharmaceutical industry, particularly for producing injectable antibiotic formulations.

Application

• Pharmaceutical API Synthesis: Primary use as the active pharmaceutical ingredient in the manufacture of sterile injectable antibiotic drugs.
• Antibacterial Formulations: Used in the development and production of broad-spectrum antibiotic products targeting respiratory, urinary tract, and intra-abdominal infections.
• Research & Development: Serves as a key reference standard and intermediate in microbiological and pharmacological research for new antibacterial agents.
• Veterinary Medicine: Potential application in the formulation of antibacterial treatments for veterinary use, subject to regional regulatory approvals.
• Hospital Compounding: May be utilized in specialized hospital pharmacy settings for preparing specific dosage forms, where legally permitted.

Basic Information

Product Name	Ceftizoxime
CAS No.	929101-89-3
Molecular Formula	C13H13N5O5S2
Molecular Weight	383.41 g/mol
Synonyms	Ceftizoxime Sodium; (6R,7R)-7-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid; FK-749; FR-13749; Ceftizox; Cefizox; Epocelin; Ceftix
EINECS	Contact for details

Quality Control

Our Ceftizoxime is manufactured under strict quality management systems. It is typically tested to meet specifications aligned with major pharmacopoeial standards such as USP and EP. Every batch undergoes rigorous analytical testing including identification, purity assay, and impurity profiling. A comprehensive Certificate of Analysis (COA) documenting all test results is provided with each shipment to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment. Recommended long-term storage temperature is between 2°C and 8°C (refrigerated). For short-term handling, the product may be kept at controlled room temperature (15-25°C).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.2%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Bacterial Endotoxins	< 0.10 EU/mg (for injectable grade)
Sterility	Conforms (for sterile grade)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.