Description

Di-tert-Butyl 2-Carbamoylpiperazine-1,4-Dicarboxylate is a high-purity, protected piperazine derivative serving as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring a versatile and reactive intermediate to construct complex molecular architectures. It is primarily utilized in the pharmaceutical and agrochemical industries for the development of novel active ingredients, particularly in medicinal chemistry programs targeting new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing functionalized piperazine cores.
• Medicinal Chemistry Research: Used as a versatile scaffold in drug discovery for building libraries of novel small molecules with potential biological activity.
• Agrochemical Synthesis: Serves as a building block in the development of new pesticides, herbicides, and fungicides.
• Peptidomimetics Development: Employed in the design and synthesis of peptide analogs and mimetics for biochemical research.
• Ligand and Catalyst Preparation: Useful for constructing specialized ligands and organocatalysts used in asymmetric synthesis.
• Custom Chemical Synthesis: A valuable starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	Di-tert-Butyl 2-Carbamoylpiperazine-1,4-Dicarboxylate
CAS No.	927883-45-2
Molecular Formula	C15H27N3O5
Molecular Weight	329.40 g/mol
Synonyms	1,4-Di-tert-butyl 2-carbamoylpiperazine-1,2,4-tricarboxylate; 2-Carbamoylpiperazine-1,4-dicarboxylic acid di-tert-butyl ester; 1,4-Bis(tert-butoxycarbonyl)-2-carbamoylpiperazine; Di-Boc-2-carbamoylpiperazine; N,N'-Di-Boc-2-carbamoylpiperazine; tert-Butyl 2-carbamoyl-4-(tert-butoxycarbonyl)piperazine-1-carboxylate; 927883-45-2; Piperazine-1,4-dicarboxylic acid, 2-carbamoyl-, 1,4-di-tert-butyl ester
EINECS	Contact for details

Quality Control

Our Di-tert-Butyl 2-Carbamoylpiperazine-1,4-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.