Description

4-(4-Ethylpiperazin-1-Yl)-3-Methoxybenzonitrile is a high-purity, advanced pharmaceutical intermediate featuring a benzonitrile core substituted with a methoxy group and an ethylpiperazine moiety. This compound is of significant commercial importance for its role as a key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and contract research organizations (CROs) engaged in developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, especially those targeting neurological receptors.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural component for APIs under investigation for psychiatric and neurological disorders.
• Chemical Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Biochemical Research: Utilized in pharmacological studies as a ligand or probe to investigate specific biological pathways.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, non-commercially available compounds for research purposes.

Basic Information

Product Name	4-(4-Ethylpiperazin-1-Yl)-3-Methoxybenzonitrile
CAS No.	927703-20-6
Molecular Formula	C14H19N3O
Molecular Weight	245.32 g/mol
Synonyms	3-Methoxy-4-(4-ethylpiperazin-1-yl)benzonitrile; 4-(4-Ethyl-1-piperazinyl)-3-methoxybenzonitrile; 927703-20-6; 3-Methoxy-4-(4-ethylpiperazin-1-yl)benzonitrile; Benzonitrile, 3-methoxy-4-(4-ethyl-1-piperazinyl)-; 4-(N-Ethylpiperazino)-3-methoxybenzonitrile
EINECS	Contact for details

Quality Control

Our 4-(4-Ethylpiperazin-1-Yl)-3-Methoxybenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis to ensure compliance with ICH guidelines. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and consistent quality for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.