Description

n-(5-Amino-2-Fluorophenyl)Cyclobutanecarboxamide is a specialized aromatic amine derivative featuring a cyclobutane carboxamide moiety. This compound is a crucial high-purity building block in advanced organic synthesis, valued for its unique structural framework that enables the development of novel molecular architectures. It is primarily utilized by pharmaceutical R&D and fine chemical sectors for the discovery and production of active pharmaceutical ingredients and other high-value intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Serves as a precursor for novel pesticides and herbicides, leveraging the fluorine and amino groups for bioactivity.
• Material Science Research: Used in the synthesis of advanced polymers and liquid crystals where specific aromatic-amide structures are required.
• Chemical Biology Probes: Employed as a scaffold for developing molecular probes and diagnostic agents due to its modifiable functional groups.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including cross-coupling and amidation reactions.

Basic Information

Product Name	n-(5-Amino-2-Fluorophenyl)Cyclobutanecarboxamide
CAS No.	926255-07-4
Molecular Formula	C11H13FN2O
Molecular Weight	208.23 g/mol
Synonyms	5-Amino-2-fluoro-N-cyclobutylbenzamide; Cyclobutanecarboxamide, N-(5-amino-2-fluorophenyl)-; 2-Fluoro-5-aminophenyl cyclobutyl ketone amine; N-Cyclobutyl-5-amino-2-fluorobenzamide; 926255-07-4; 5-Amino-2-fluorobenzocyclobutane carboxamide; 2-Fluoro-5-aminocyclobutylbenzamide
EINECS	Contact for details

Quality Control

Our n-(5-Amino-2-Fluorophenyl)Cyclobutanecarboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing purity, impurity profile, and other critical parameters are provided to guarantee batch-to-batch consistency and suitability for your sensitive synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.