Description

3′-o-Allyl Dc CAS NO 925915-24-8 is a high-purity nucleoside derivative, a critical building block in oligonucleotide synthesis and pharmaceutical research. Its primary value lies in enabling the precise modification of nucleic acid structures, which is essential for developing advanced therapeutics and diagnostic tools. This compound is specifically required by research institutions and manufacturers in the fields of antisense oligonucleotide (ASO) development, siRNA synthesis, and medicinal chemistry for creating novel drug candidates.

Application

• Oligonucleotide Synthesis: A key phosphoramidite monomer for the solid-phase synthesis of modified DNA/RNA strands.
• Antisense & siRNA Therapeutics: Used in the research and production of therapeutic oligonucleotides targeting specific genes.
• Medicinal Chemistry & Drug Discovery: Serves as a crucial intermediate for developing nucleoside-based prodrugs and antiviral agents.
• Bioconjugation & Probe Development: The allyl group provides a handle for further chemical modifications and labeling for diagnostic probes.
• Academic & Industrial R&D: Fundamental research tool for studying nucleic acid structure, function, and stability.

Basic Information

Product Name	3′-o-Allyl Dc CAS NO 925915-24-8
CAS No.	925915-24-8
Molecular Formula	C12H15N3O5
Molecular Weight	281.26 g/mol
Synonyms	3′-O-Allyl-2′-deoxycytidine; 3′-O-Allyldeoxycytidine; 1-(3-O-Allyl-2-deoxy-β-D-erythro-pentofuranosyl)-4-aminopyrimidin-2(1H)-one; 2′-Deoxycytidine, 3′-O-2-propen-1-yl-; Allyl Deoxycytidine; 3′-O-Allyl-dC; 3′-Allyloxy-2′-deoxycytidine
EINECS	Contact for details

Quality Control

Our 3′-o-Allyl Dc is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for sensitive research and production applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of GMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Solubility	Soluble in DMSO, DMF; Slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.