Description

Guanosine 5'-Triphosphate Trisodium Salt is a high-purity nucleotide essential for cellular energy transfer and signal transduction. This critical biochemical serves as a substrate for RNA polymerases and a vital cofactor for numerous enzymatic reactions, including protein synthesis and metabolic regulation. It is indispensable for researchers and manufacturers in the life sciences, pharmaceutical development, and diagnostic kit production.

Application

• Biochemical Research & In Vitro Diagnostics (IVD): A fundamental substrate for enzymatic assays, PCR master mixes, and cell-based studies to investigate metabolic pathways and gene expression.
• Pharmaceutical Development: Used in the synthesis of nucleotide analogs and as a critical component in cell culture media for biopharmaceutical production, including monoclonal antibodies and vaccines.
• Molecular Biology Reagents: An essential building block for in vitro transcription (IVT) systems to produce mRNA, RNA probes, and other RNA molecules.
• Enzymology Studies: Serves as a primary energy source (phosphate donor) for kinases, GTPases, and other ATP-dependent enzymes in mechanistic and kinetic studies.
• Diagnostic Kit Manufacturing: A key raw material in the formulation of kits for clinical diagnostics, including those for infectious diseases, genetic disorders, and cancer biomarkers.
• Cell Signaling & Neuroscience Research: Utilized in studies of G-protein coupled receptor (GPCR) pathways and other GTP-dependent signaling cascades.

Basic Information

Product Name	Guanosine 5'-Triphosphate Trisodium Salt
CAS No.	36051-31-7
Molecular Formula	C10H14N5Na3O14P3
Molecular Weight	605.13 g/mol (anhydrous basis)
Synonyms	GTP Trisodium Salt; Guanosine-5'-triphosphate trisodium salt; 5'-GTP Na3; Sodium Guanosine Triphosphate; Guanosine triphosphate trisodium salt hydrate; Disodium 5'-guanylyl triphosphate; 2-Amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-3H-purin-6-one triphosphate trisodium salt
EINECS	Contact for details

Quality Control

Our Guanosine 5'-Triphosphate Trisodium Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and diagnostic applications. Certificates of Analysis (COA) detailing purity, endotoxin levels, and other critical parameters are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the container to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC/UV)	Conforms
Purity (HPLC)	≥ 95%
pH (1% Solution)	6.0 - 8.0
Water Content (KF)	≤ 5.0 %
Endotoxin	< 10 EU/mg
Solubility	Soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.