Description

Guanosine 3'-(Dihydrogen Phosphate) is a key nucleotide monophosphate derivative essential for RNA synthesis and various biochemical pathways. This high-purity compound is critical for research and development in life sciences, where precise biochemical function and structural integrity are paramount. It is primarily utilized by pharmaceutical researchers, diagnostic kit manufacturers, and academic institutions for applications in molecular biology, enzymology, and as a building block for oligonucleotide synthesis.

Application

• Biochemical Research & Enzymology: Serves as a substrate or intermediate in enzymatic studies, particularly those involving kinases, phosphatases, and polymerases.
• Oligonucleotide Synthesis: Acts as a crucial raw material (phosphoramidite precursor) in the solid-phase synthesis of RNA oligonucleotides for therapeutic and diagnostic applications.
• Pharmaceutical Development: Used in the research and development of nucleotide-based antiviral drugs and other therapeutic agents.
• Diagnostic Reagents: Incorporated into the formulation of reagents for molecular diagnostics, including PCR and other nucleic acid amplification techniques.
• Cell Culture & Media Supplements: Employed as a defined component in specialized cell culture media to support specific metabolic studies.
• Reference Standard: Used as a high-purity analytical standard in HPLC, LC-MS, and other chromatographic methods for quality control and quantification.

Basic Information

Product Name	Guanosine 3'-(Dihydrogen Phosphate)
CAS No.	117-68-0
Molecular Formula	C10H14N5O8P
Molecular Weight	363.22 g/mol
Synonyms	3'-GMP; Guanosine 3'-monophosphate; 3'-Guanylic acid; Guanylic acid (3'-); GMP (3'-); 9-β-D-Ribofuranosylguanine 3'-(dihydrogen phosphate); Guanosine 3'-phosphate; 117-68-0
EINECS	204-215-8

Quality Control

Our Guanosine 3'-(Dihydrogen Phosphate) is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production standards. Specifications can meet the requirements for use as a pharmaceutical intermediate or high-grade biochemical.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Solubility	Soluble in water, slightly soluble in ethanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.