Description

Guanine CAS NO 73-40-5 is a fundamental purine nucleobase, essential for the structure of nucleic acids DNA and RNA. Its high-purity form is critical for ensuring the integrity and performance of biochemical research, diagnostic assays, and pharmaceutical development. This compound is primarily required by manufacturers and research institutions in the biotechnology, pharmaceutical, and molecular diagnostics sectors for applications ranging from oligonucleotide synthesis to cell culture media supplementation.

Application

• Nucleic Acid Research & Synthesis: A key building block (nucleobase) for the chemical synthesis of oligonucleotides, primers, and probes.
• Pharmaceutical Intermediates: Used in the production of antiviral drugs (e.g., Acyclovir derivatives) and other nucleoside-based therapeutics.
• Cell Culture & Microbiology: Incorporated into defined cell culture media and microbial growth media as a nutritional component.
• Diagnostic Reagents: Serves as a raw material in the formulation of reagents for molecular diagnostic tests and kits.
• Biochemical Standards: Utilized as a high-purity standard or reference material in analytical laboratories for HPLC, LC-MS, or UV calibration.
• Cosmetic & Personal Care: Employed in premium skincare formulations for its purported skin-conditioning properties, often derived from natural sources like pearl essence.

Basic Information

Product Name	Guanine
CAS No.	73-40-5
Molecular Formula	C5H5N5O
Molecular Weight	151.13 g/mol
Synonyms	2-Amino-1,7-dihydro-6H-purin-6-one; 2-Amino-6-hydroxypurine; 2-Aminohypoxanthine; Guanine Base; CI 75170; Natural White 1; Pearl Essence; G (IUPAC single-letter abbreviation)
EINECS	200-799-8

Quality Control

Our Guanine is produced and tested under a strict quality management system to ensure batch-to-batch consistency and high purity suitable for research and industrial applications. We provide comprehensive analytical data, including HPLC purity, residual solvent analysis, and heavy metal limits. A Certificate of Analysis (COA) is supplied with each batch, and custom synthesis to meet specific pharmacopeial standards (e.g., USP, EP) or customer specifications is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.