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2-Fluoroadenosine CAS NO 146-78-1


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CAS No.:146-78-1

Grade:Pharmacy Grade

Content:99.0%

Brand:Customizable

Packaging:Customizable

Description

2-Fluoroadenosine is a fluorinated nucleoside analog of adenosine, a key building block in medicinal chemistry and biochemical research. Its primary value lies in its role as a versatile intermediate for synthesizing modified oligonucleotides and potential pharmaceutical agents. This compound is essential for researchers and manufacturers in the fields of nucleoside chemistry, antiviral drug development, and molecular biology. The product is supplied as 2-Fluoroadenosine CAS NO 146-78-1, meeting the stringent purity requirements of advanced R&D and production.

Application

  • Pharmaceutical Intermediate: A critical precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
  • Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate adenosine receptor pathways and nucleotide metabolism.
  • Oligonucleotide Synthesis: Serves as a modified building block for creating fluorinated DNA or RNA strands for diagnostic probes and therapeutic aptamers.
  • Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to develop new drug candidates with enhanced stability and binding affinity.
  • Academic Research: Utilized in universities and research institutes for fundamental studies in chemical biology and epigenetics.

Basic Information

Product Name 2-Fluoroadenosine
CAS No. 146-78-1
Molecular Formula C10H12FN5O4
Molecular Weight 285.24 g/mol
Synonyms 2-Fluoroadenosine; 9-β-D-Ribofuranosyl-2-fluoroadenine; 2-F-Ade; 2-Fluoroadenine riboside; 2-Fluoroadenosine-9-β-D-ribofuranoside; 2-Fluoroadenine-9-β-D-ribofuranoside; 2-FA; Adenosine, 2-fluoro-
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Quality Control

Our 2-Fluoroadenosine is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed in a desiccated environment to prevent degradation. For long-term storage, consider conditions of 2-8°C.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Conforms to reference standard
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.

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