Description

Inosine 5'-(Tetrahydrogen Triphosphate) (CAS NO 132-06-9) is a high-purity nucleotide triphosphate analog essential for biochemical research and diagnostic applications. Its primary value lies in serving as a substrate for enzymes like polymerases and kinases, enabling studies in molecular biology, virology, and cell signaling pathways. This compound is critically needed by research institutions, pharmaceutical developers, and diagnostic kit manufacturers for applications ranging from enzymatic assays to the development of novel therapeutic agents.

Application

• Enzymatic Substrate for Research: Used as a critical substrate in studies involving RNA polymerases, kinases, and other nucleotide-dependent enzymes to investigate mechanism and inhibition.
• Molecular Biology & Virology: Employed in in vitro transcription and replication assays to study viral polymerases and develop antiviral screening platforms.
• Diagnostic Reagent Manufacturing: A key component in the formulation of enzymatic diagnostic kits, including those for monitoring cellular energy metabolism (ATP-related pathways).
• Biochemical Assay Development: Integral to high-throughput screening (HTS) assays and signal amplification systems in drug discovery and life science research.
• Cell Signaling & Metabolism Studies: Utilized to probe purinergic signaling pathways and nucleotide metabolism within cells.
• Reference Standard: Serves as a high-purity analytical standard for quality control in pharmaceutical and diagnostic manufacturing.

Basic Information

Product Name	Inosine 5'-(Tetrahydrogen Triphosphate)
CAS No.	132-06-9
Molecular Formula	C10H15N4O14P3
Molecular Weight	508.18 g/mol
Synonyms	ITP; Inosine Triphosphate; 5'-ITP; Inosine 5'-triphosphate; 9-β-D-Ribofuranosylhypoxanthine 5'-(tetrahydrogen triphosphate); Inosine-5'-triphosphoric acid; NSC 20264; 5'-Inosinic triphosphate
EINECS	205-051-7

Quality Control

Our Inosine 5'-(Tetrahydrogen Triphosphate) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and diagnostic use. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to keep the material desiccated. Allow the container to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/UV)	Conforms
Purity (HPLC)	≥ 95%
Water Content (Karl Fischer)	≤ 5.0 %
pH (1% Solution)	5.0 - 7.0
Endotoxin (LAL)	< 10 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.