Description

4-Chloro-2,6-Difluorophenylboronic Acid is a high-purity organoboron compound that serves as a critical building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation, which is essential for creating complex molecular architectures. This boronic acid is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key reagent in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific halogenated aromatic structures.
• Material Science Research: Employed in the development of organic electronic materials, such as polymers for OLEDs and semiconductors, where its difluoro and chloro substituents modify electronic properties.
• Ligand and Catalyst Preparation: Acts as a precursor for creating specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes and diagnostics.
• Custom Synthesis & Contract Manufacturing: Serves as a starting material for custom synthesis services catering to R&D and pilot-scale production needs.

Basic Information

Product Name	4-Chloro-2,6-Difluorophenylboronic Acid
CAS No.	925911-61-1
Molecular Formula	C6H4BClF2O2
Molecular Weight	191.36 g/mol
Synonyms	(4-Chloro-2,6-difluorophenyl)boronic acid; 4-Chloro-2,6-difluorobenzeneboronic acid; 2,6-Difluoro-4-chlorophenylboronic acid; B-(4-Chloro-2,6-difluorophenyl)boronic acid; 925911-61-1; 4-Cl-2,6-F2-PhB(OH)2
EINECS	Contact for details

Quality Control

Our 4-Chloro-2,6-Difluorophenylboronic Acid is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.