Description

3,4-Difluoro-5-Methoxybenzeneboronic Acid is a high-purity boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in enabling precise Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used to create novel, fluorinated herbicides, fungicides, and pesticides with enhanced biological activity and environmental stability.
• Material Science Research: Building block for developing organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport materials.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and sensors for diagnostic and research applications.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Item	Details
Product Name	3,4-Difluoro-5-Methoxybenzeneboronic Acid
CAS No.	925910-42-5
Molecular Formula	C7H7BF2O3
Molecular Weight	187.94 g/mol
Synonyms	(3,4-Difluoro-5-methoxyphenyl)boronic acid; 3,4-Difluoro-5-methoxybenzeneboronic acid pinacol ester (protected form); 5-Methoxy-3,4-difluorobenzeneboronic acid; Boronic acid, B-(3,4-difluoro-5-methoxyphenyl)-; 925910-42-5; 3,4-Difluoro-5-methoxy phenylboronic acid
EINECS	Contact for details

Quality Control

Every batch of 3,4-Difluoro-5-Methoxybenzeneboronic Acid is manufactured under strict quality management systems. We ensure high purity and batch-to-batch consistency through comprehensive analytical testing, including NMR, HPLC, and elemental analysis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.