Description

5-Bromo-2-Cyanobenzeneacetonitrile is a versatile and high-purity brominated aromatic nitrile building block. This compound is valued for its bifunctional reactivity, offering distinct sites for nucleophilic substitution and cyano group transformations. It is primarily sought after by research chemists and process development teams in the pharmaceutical and agrochemical sectors. Its structural features make it a critical intermediate for synthesizing complex molecules, including active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging the bromine atom for further functionalization.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the construction of organic electronic materials, such as non-fullerene acceptors for organic photovoltaics (OPVs).
• Chemical Biology Probes: Utilized to build molecular probes and tags for studying enzyme activity and cellular processes.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	5-Bromo-2-Cyanobenzeneacetonitrile
CAS No.	925672-88-4
Molecular Formula	C9H5BrN2
Molecular Weight	221.06 g/mol
Synonyms	2-(5-Bromo-2-cyanophenyl)acetonitrile; (5-Bromo-2-cyanophenyl)acetonitrile; 5-Bromo-2-cyanobenzyl cyanide; 2-Cyano-5-bromobenzyl cyanide; 5-Bromo-2-cyanophenylacetonitrile; α-(5-Bromo-2-cyanophenyl)acetonitrile; 925672-88-4; 5-Bromo-2-cyanobenzeneacetonitrile
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-2-Cyanobenzeneacetonitrile is produced and tested under a strict quality management system. We guarantee high chemical purity and lot-to-lot consistency, which is critical for your synthetic workflows. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.