Description

1-(Boc-Amino)-3-Bromo-1-(4-Bromophenyl)Propane is a specialized, high-purity brominated organic building block featuring both a Boc-protected amine and an aromatic bromide functional group. This compound matters for its role as a critical intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in medicinal chemistry programs targeting new therapeutic agents.
• Peptidomimetic Synthesis: Utilized in the construction of peptidomimetics and modified peptide chains where the Boc group provides orthogonal protection for the amine functionality.
• Cross-Coupling Reactions: Serves as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) due to the reactive aromatic bromide moiety.
• Agrochemical Research: Intermediate in the development of novel herbicides, fungicides, and insecticides requiring specific brominated aromatic structures.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for catalysis or as a precursor for functionalized materials.
• Chemical Biology Probes: Building block for creating labeled compounds or probes used in biochemical and cellular studies.

Basic Information

Product Name	1-(Boc-Amino)-3-Bromo-1-(4-Bromophenyl)Propane
CAS No.	924817-79-8
Molecular Formula	C14H19Br2NO2
Molecular Weight	393.11 g/mol
Synonyms	1-(tert-Butoxycarbonylamino)-3-bromo-1-(4-bromophenyl)propane; tert-Butyl N-[3-bromo-1-(4-bromophenyl)propyl]carbamate; 3-Bromo-1-(4-bromophenyl)-1-[(tert-butoxycarbonyl)amino]propane; 1-(Boc-amino)-3-bromo-1-(p-bromophenyl)propane; N-Boc-3-bromo-1-(4-bromophenyl)propylamine; (3-Bromo-1-(4-bromophenyl)propyl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 1-(Boc-Amino)-3-Bromo-1-(4-Bromophenyl)Propane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.