Description

2-Chloro-4-Fluoro-5-Methylbenzonitrile is a high-purity, multi-functional aromatic nitrile building block of significant importance in advanced organic synthesis. Its molecular structure, featuring chloro, fluoro, and methyl substituents on a benzonitrile core, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and industrial manufacturers in the agrochemical and pharmaceutical sectors for the development of novel active ingredients and fine chemicals.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of modern herbicides, fungicides, and insecticides, where the halogen and nitrile groups contribute to biological activity.
• Pharmaceutical Building Block: Used in medicinal chemistry for the research and development of new drug candidates, particularly in creating molecules with specific steric and electronic profiles.
• Ligand and Catalyst Synthesis: Serves as a starting material for the preparation of specialized ligands used in catalytic processes and material science applications.
• Functional Material Development: Employed in the synthesis of advanced polymers, liquid crystals, and organic electronic materials due to its rigid, substituted aromatic structure.
• Custom Synthesis and R&D: A valuable reagent for contract research organizations and academic labs exploring novel chemical transformations and heterocyclic chemistry.

Basic Information

Product Name	2-Chloro-4-Fluoro-5-Methylbenzonitrile
CAS No.	924626-79-9
Molecular Formula	C8H5ClFN
Molecular Weight	169.58 g/mol
Synonyms	2-Chloro-4-fluoro-5-methylbenzonitrile; 5-Methyl-2-chloro-4-fluorobenzonitrile; Benzonitrile, 2-chloro-4-fluoro-5-methyl-; 924626-79-9; 2-Chloro-4-fluoro-5-methyl-benzonitrile
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-4-Fluoro-5-Methylbenzonitrile is manufactured and tested under a strict quality management system. We ensure the product meets high-purity standards suitable for research and industrial synthesis. Comprehensive analytical testing, including HPLC, GC, and NMR, is performed to verify identity, purity, and impurity profiles. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be stored away from direct light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.