Description

Alanine, 2-Methyl-n-(3,3,3-Trifluoro-1-Oxopropyl)- is a specialized fluorinated amino acid derivative, a high-value building block in advanced organic synthesis. Its core value proposition lies in the strategic incorporation of a trifluoromethyl ketone moiety, which is critical for modulating the physicochemical and metabolic properties of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for creating novel active ingredients with enhanced stability and bioavailability.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of protease inhibitors, enzyme modulators, and other bioactive molecules where the trifluoromethyl group improves metabolic stability and lipophilicity.
• Agrochemical Research: Used in developing advanced herbicides, fungicides, and pesticides, leveraging the fluorine atoms to enhance biological activity and environmental persistence.
• Peptidomimetics & Drug Design: Incorporated into peptide backbones to create analogs resistant to enzymatic degradation, aiding in the development of novel therapeutic peptides.
• Chemical Biology Probes: Serves as a tagged amino acid derivative for studying enzyme mechanisms or protein-protein interactions in biochemical research.
• Material Science Precursor: Potential use in synthesizing specialized fluorinated polymers or coatings with unique surface properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules under cGMP conditions.

Basic Information

Product Name	Alanine, 2-Methyl-n-(3,3,3-Trifluoro-1-Oxopropyl)-
CAS No.	923972-69-4
Molecular Formula	C7H10F3NO3
Molecular Weight	213.16 g/mol
Synonyms	2-Methylalanine N-(3,3,3-trifluoropropanoyl) derivative; N-(3,3,3-Trifluoropropanoyl)-2-methylalanine; 2-Amino-N-(3,3,3-trifluoro-1-oxopropyl)butanoic acid; (2S)-2-Amino-N-(3,3,3-trifluoropropanoyl)butanoic acid (for stereoisomer); 3,3,3-Trifluoro-N-(1-carboxypropyl)propanamide; TFMK-Alanine derivative; 923972-69-4 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our Alanine, 2-Methyl-n-(3,3,3-Trifluoro-1-Oxopropyl)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis (if applicable), and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment. We can support development projects requiring compliance with ICH guidelines or other relevant regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.