Description

Benzyl n-(3,3-Difluorocyclohexyl)Carbamate CAS NO 921602-76-8 is a specialized fluorinated carbamate derivative, serving as a high-value synthetic intermediate in advanced organic synthesis. Its core value lies in the strategic incorporation of fluorine atoms and a protected amine functionality, which are critical for modulating the physicochemical and biological properties of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for constructing novel active ingredients and exploring structure-activity relationships.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting CNS disorders, metabolic diseases, and oncology.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the difluorocyclohexyl moiety can enhance bioavailability and environmental stability.
• Fluorine Chemistry: A valuable reagent for introducing fluorine-containing fragments into complex molecules to improve metabolic stability, lipophilicity, and membrane permeability.
• Peptidomimetics & PROTACs: Serves as a precursor for constructing non-peptide scaffolds and linkers in Proteolysis Targeting Chimeras (PROTACs) and other bifunctional molecules.
• Material Science: Potential monomer or additive for creating specialty polymers with unique surface properties and chemical resistance.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development in organic synthesis and fluorine chemistry.

Basic Information

Product Name	Benzyl n-(3,3-Difluorocyclohexyl)Carbamate
CAS No.	921602-76-8
Molecular Formula	C14H17F2NO2
Molecular Weight	269.29 g/mol
Synonyms	Benzyl (3,3-difluorocyclohexyl)carbamate; Carbamic acid, N-(3,3-difluorocyclohexyl)-, phenylmethyl ester; 3,3-Difluorocyclohexylcarbamic acid benzyl ester; N-(3,3-Difluorocyclohexyl)carbamic Acid Benzyl Ester; Benzyl N-(3,3-Difluorocyclohexyl)carbamate; (3,3-Difluorocyclohexyl)carbamic Acid Benzyl Ester; BnOCO-NH-C6H9F2 (Abbrev.)
EINECS	Contact for details

Quality Control

Our Benzyl n-(3,3-Difluorocyclohexyl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic intermediates. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We support compliance with relevant guidelines for pharmaceutical development (ICH Q7, GMP where applicable).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified for long-term storage. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.