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S-N,n-Dimethyl-[1,1'-Binaphthalene]-2,2'-Diamine CAS NO 921212-80-8
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CAS No.:921212-80-8
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
S-N,n-Dimethyl-[1,1'-Binaphthalene]-2,2'-Diamine is a chiral diamine derivative of 1,1'-binaphthyl, a privileged scaffold in asymmetric synthesis. This compound matters as a sophisticated ligand precursor and chiral building block, enabling the creation of highly selective catalysts for enantioselective transformations. It is primarily needed by research institutions and fine chemical manufacturers developing advanced pharmaceuticals, agrochemicals, and specialty materials where precise stereochemical control is critical. The product is supplied with a high level of purity to meet the stringent demands of modern synthetic chemistry.
Application
- As a key chiral precursor for the synthesis of axially chiral ligands used in asymmetric catalysis (e.g., hydrogenation, cross-coupling).
- In the research and development of pharmaceutical intermediates, particularly for active pharmaceutical ingredients (APIs) requiring specific enantiomeric purity.
- As a building block for functionalized materials, such as chiral polymers or liquid crystals with advanced optical properties.
- In academic and industrial R&D for exploring novel reaction methodologies and catalyst systems.
- For the preparation of analytical reagents and chiral selectors used in chromatography for enantiomer separation.
Basic Information
| Product Name | S-N,n-Dimethyl-[1,1'-Binaphthalene]-2,2'-Diamine |
| CAS No. | 921212-80-8 |
| Molecular Formula | C22H20N2 |
| Molecular Weight | 312.41 g/mol |
| Synonyms | (S)-N,N-Dimethyl-1,1'-binaphthalene-2,2'-diamine; (S)-2,2'-Bis(dimethylamino)-1,1'-binaphthyl; (S)-DM-BINAM; (S)-(-)-2,2'-Bis(N,N-dimethylamino)-1,1'-binaphthyl; (S)-N,N,N',N'-Tetramethyl-1,1'-binaphthyl-2,2'-diamine; (S)-(-)-DM-BINAM; (S)-2,2'-Di(N,N-dimethylamino)-1,1'-binaphthyl; (S)-Axially Chiral Diamine |
| EINECS | Contact for details |
Quality Control
Our S-N,n-Dimethyl-[1,1'-Binaphthalene]-2,2'-Diamine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) determination and standard purity assays, to ensure compliance with research and development grade specifications. Certificates of Analysis (COA) documenting identity, purity, and chiral purity are available upon request to support your quality assurance processes.
Storage
Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at room temperature (15-25°C). This compound is easily oxidized; prolonged exposure to air should be avoided. Keep away from heat and incompatible materials.
Specification
| Item | Specification |
|---|---|
| Appearance | Off-white to light yellow crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Enantiomeric Excess (Chiral HPLC) | ≥ 98.0% ee |
| Melting Point | Contact for details |
| Loss on Drying | ≤ 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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