Description

(R,R)-(+)-1,2-Bis(T-Butylmethylphosphino)Benzene, commonly known as (R,R)-Benzp*, is a highly specialized, chiral bisphosphine ligand of significant importance in asymmetric catalysis. Its value lies in its ability to induce high enantioselectivity in transition metal-catalyzed reactions, enabling the production of single-enantiomer compounds with precision. This product is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries who are developing advanced synthetic routes for active pharmaceutical ingredients (APIs) and other high-value chiral molecules.

Application

• Asymmetric Hydrogenation: A premier ligand for the enantioselective hydrogenation of prochiral olefins, ketones, and imines, a key step in API synthesis.
• Pharmaceutical Intermediate Synthesis: Critical for constructing chiral centers in complex drug molecules, including those for cardiovascular, CNS, and antiviral therapies.
• Agrochemical Production: Used in the synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Manufacturing: Enables the production of specialty flavors, fragrances, and advanced materials with specific chiral properties.
• Academic & Industrial R&D: A valuable tool for methodology development and exploring new catalytic transformations in both university and corporate research laboratories.
• Catalyst Ligand Screening Kits: Supplied as a high-purity component in kits for screening optimal catalytic conditions for challenging transformations.

Basic Information

Product Name	(R,R)-(+)-1,2-Bis(T-Butylmethylphosphino)Benzene ((R,R)-Benzp*)
CAS No.	919778-41-9
Molecular Formula	C20H36P2
Molecular Weight	338.43 g/mol
Synonyms	(R,R)-Benzp*; (R,R)-1,2-Bis(tert-butylmethylphosphino)benzene; (R,R)-1,2-Bis[(tert-butyl)methylphosphino]benzene; (R,R)-DTBMPB; (R,R)-Bisphosphine Benzene Ligand; (R,R)-Josiphos-type ligand analog; (1R,2R)-1,2-Bis[(tert-butyl)(methyl)phosphanyl]benzene
EINECS	Contact for details

Quality Control

Every batch of (R,R)-Benzp* is manufactured and analyzed under strict quality management protocols to ensure exceptional purity and chiral integrity, critical for reproducible catalytic performance. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing full transparency on chiral purity, chemical purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., argon or nitrogen) at 2-8°C or as specified on the label. Due to its sensitivity to oxidation and moisture, the container should only be opened in a controlled, dry, and oxygen-free environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Specific Rotation	Contact for details
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.