Description

Cyclopropanecarboxylic Acid, 1-[[(2-Fluorophenyl)Amino]Carbonyl]- (CAS 918642-61-2) is a specialized fluorinated cyclopropane derivative that serves as a critical synthetic intermediate in advanced organic chemistry. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate the unique steric and electronic properties of the cyclopropane ring into target molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in medicinal chemistry programs targeting central nervous system (CNS) disorders, inflammation, or metabolic diseases.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, or insecticides, where the cyclopropane moiety can enhance biological activity and environmental stability.
• Fine Chemical Synthesis: Serves as a versatile precursor for creating complex fluorinated organic compounds used in materials science, catalysis, and specialty polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms or protein-ligand interactions due to its defined stereochemistry and fluorine label.
• Academic & Contract Research: Essential reagent for methodological development in organic synthesis laboratories focused on amide bond formation and cyclopropane chemistry.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 1-[[(2-Fluorophenyl)Amino]Carbonyl]-
CAS No.	918642-61-2
Molecular Formula	C11H10FNO2
Molecular Weight	207.20 g/mol
Synonyms	1-[(2-Fluorophenyl)carbamoyl]cyclopropanecarboxylic acid; N-(2-Fluorophenyl)cyclopropane-1,1-dicarboxamide; Cyclopropane-1,1-dicarboxylic acid mono-(2-fluoroanilide); 2-Fluoro-N-(1-carboxycyclopropanecarbonyl)aniline; 918642-61-2; FC-CPDCA; 2-Fluorophenyl-cyclopropanedicarboximide acid
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 1-[[(2-Fluorophenyl)Amino]Carbonyl]- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and scale-up activities. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.